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A supplementation with methylfolate alone is not always effective, as it has to interact closely with vitamin B12

Vitamin B12 is included in injections like these because its an important nutrient for the body

The authors identified future areas of investigation including male models, long-term treatment effects, and combination with other NAD+ precursors such as NMN

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A double-blind placebo-controlled clinical trial of subcutaneous recombinant human ciliary neurotrophic factor (rHCNTF) in amyotrophic lateral sclerosis
