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It was also discussed that certain drugs and, generally, several other substances can affect a tests results, but referring to these interfering factors, we cannot know what exactly exists inside the patients organism at a microenvironmental level, so as to predict possible misdiagnoses

Feb 6 2024;83(5):549-558

This adaptability enables macrophage polarization, which is the process by which macrophages mount a specific phenotypic and functional response to the microenvironmental stimuli encountered in a specific tissue (Sica and Mantovani, 2012)
