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Current Neuropharmacology 2016 Sikiri et al

Verify your body's response with bloodwork at 8 to 12 week intervals

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Most patients notice the first changes within two weeks: Pain reduction and decreased inflammation come first, followed by improved range of motion and faster recovery as the protocol progresses

2021;34(11):1665-1675.e6

However, this was primarily the case for grade 3 disc degeneration (n = 3), where still strong statistical differences could be identified and for which the range of motion was generally very low in all three primary motion directions, as severe disc degeneration is usually associated with an immobilization of the motion segment due to very low disc height and bridging osteophytes (Fig