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During this time, researchers typically monitor a range of indicators

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Control of skin blood flow, sweating, and heart rate: role of skin vs

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Because of the incomplete clinical evidence on their effectiveness, safety, and social consequences in the case of long-term use, especially with synthetic variants of these drugs, they cannot be recommended to healthy individuals who do not suffer from any cognitive dysfunction

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The combination group had the best effect, with cartilage close to normal

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Coluzzi F, Rullo L, Scerpa MS, Losapio LM, Rocco M, Billeci D, Candeletti S, Romualdi P (2022) Current and future therapeutic options in pain management: multi-mechanistic opioids involving both MOR and NOP receptor activation

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