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Curcumin: a review for health benefits

Loss- or gain-of-function studies of Notch/RBPjk signaling showed that chondrogenesis was either enhanced or impaired, respectively, in mouse embryos

Korell, F., Berger, T

Other studies have shown that this process also involves inhibition of the expression of MCT4 (113), stimulation of the mitochondrial metabolism (114), and shifting glucose consumption from lactic acid production to the pentose phosphate pathway (115)
This is especially the case after the loading period is finished, to help determine the right frequency thereafter

Regular follow-up should include assessment of weight loss trajectory, tolerability, medication adherence, and renal function if significant GI symptoms occur
