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Traditional healers use Carica papaya seeds as a remedy for diseases and as a contraceptive for men and abortion in women

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PCOS model was established by orally administering letrozole to rats, which confirmed that Shaoyao-Gancao Decoction significantly reduced the ratio of Firmicutes to Bacteroidetes, decreased the LPS-producing pathogen Proteobacteria, increased the abundance of Butyricicoccus, Coprococcus, Akkermansia, Blautia and Bacteroides, and improved the polycystic symptoms in PCOS rats (49)

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Cirrhosis can also cause complications such as hepatic encephalopathy, portal hypertension, portal vein thrombosis, and hepatorenal syndrome

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