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Safety remains a major concern, particularly with respect to long-term exposure, immunogenicity, and the accumulation of nanomaterials in the brain or peripheral organs (Gao et al., 2026)

doi: 10.1093/nutrit/nuac094
Thus, this peptide, which is a potent CGRP receptor antagonist, can be formulated as a dry powder with no loss of activity, indicating its potential as a nasally formulated anti-migraine medicine

Each group plays a specific role
