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Aboudounya and Heads, 2021) and could facilitate increased viral replication

Recent studies indicate that while the incidence of PD is lower in younger individuals, there is a trend towards the development of the disease even in populations traditionally considered to be of lowered risk (Willis et al., 2022)

The effect of glycyrrhizin is similar to that observed with the angiotensin receptor inhibitior, candesartan, which has been shown to ameliorate ischemia-associated neuroinflammation through inhibition of TLR2 and TLR4 signaling cascades in mice (Barakat et al., 2014)

To what extent do the DAMP patterns of pathologies associated with sterile inflammation overlap

Notably, AhR activation plays a dual role in lipid peroxidation-ferroptosis axis, with distinct regulatory effects depending on the specific ligands (42)