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J Am Coll Cardiol (2004) 43:13437.10.1016/j.jacc.2003.10.060 166 GallettiFCupiniLMCorbelliICalabresiPSarchielliP

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Deprotection of 47 to furnish an inhibitor with a carboxylate in the C-terminal exhibited a somewhat lower binding affinity for IRAP (IC50 = 296 nM)

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Based on the literatures identified, a total of five botanical drugs and three polyherbal formulations were included and discussed in this review, which yields useful information regarding the mechanism of different botanical drugs and polyherbal formulations in exerting anti-uterine fibroid activity for its potential use as an alternative treatment choice for uterine fibroids

However, sex differences were not assessed, and prebiotic efficacy may vary by sex