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2013;10:e1001372

doi: 10.1016/j.intimp.2012.11.019

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Aptamer-targeted delivery of Bcl-xL shRNA using alkyl modified PAMAM dendrimers into lung cancer cells

Among these, Avasopasem manganese (GC4419), a synthetic SOD mimetic, has advanced to phase 2 clinical trials 37 , demonstrating radioprotective effects and significantly reducing the duration, severity, and incidence of severe OM

By monitoring the inflammatory responses, such as cytokine secretion and receptor activation, various biomarkers can give us an indication of the possibility of a safe and efficient transport of copper through skin to exert its beneficial effects
