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Responder (R) and Non-Responder (NR) groups were defined using a zero-centered threshold on the z-scored WRS (R 10% of body weight which would require euthanasia via protocol

Furthermore, we identify associations linking variation in both GLP1R and GIPR to GLP1 medication-related nausea or vomiting, with the GIPR association being restricted to people using tirzepatide

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In human studies, the product has also been shown to improve sleep quality, shorten bedtime, prolong sleep time, and reduce nighttime awakenings

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