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At 4 mg, the relative risk of diarrhea was 1.64 compared to placebo, with a 95% confidence interval of 0.77 to 3.49

doi: 10.1007/s00595-016-1341-5 22

People with active pancreatitis or a history of pancreatitis should approach tirzepatide with extreme caution and only under close medical supervision

The activity of PKC is regulated by various factors, including signaling molecules on the cell membrane, secondary messengers, and interactions with other proteins

(2014) Carrier-mediated cocaine transport at the bloodbrain barrier as a putative mechanism in addiction liability

For example, more of a binding protein called IGFBP3 was related to a higher risk of colorectal cancer in older men [8]