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A meta-analysis of various studies found that topical Vitamin C can significantly reduce melanin production and improve skin brightness

It has the modern name of the Mpemba Effect, named for Erasto Mpemba, a Tanzanian high school student with an interesting story

10.1002/jnr.21204 126 RamaekersV.BlauN.SequeiraJ.NassogneM.-C.QuadrosE

Over recent years, and owing to an increase in Cd pollution, an increasing number of studies have begun to investigate the impact of Cd on the growth and development of the potato by applying biochemical and molecular genetics methods [35]

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This link might partially be explained by considering that the intimately entwined glucose and glutamine metabolic pathways cooperatively support the TCA cycle and that glutamine performs diverse functions for maintaining cellular homeostasis
