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and ferroportin (FPN), whose expression is suppressed to reduce iron export ( Ferritinophagy, a selective autophagic process mediated by the cargo receptor NCOA4, plays a pivotal role in iron release by targeting ferritin for lysosomal degradation ( Additional systemic and local factors further modulate iron homeostasis

doi: 10.3390/ijms25010206 [DOI] [PMC free article] [PubMed] [Google Scholar] 24.Wright DJ, Renoir T, Smith ZM, et al

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Their potential interactions with both hypothalamicpituitary pathways and peripheral metabolic markers continue to be evaluated, although the mechanistic basis of the blend remains an active area of study

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