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Functional connectivity of specific brain regions may be more relevant to disease progression: a recent study assessing resting state functional connectivity of the striatum showed differences in spatial connectivity patterns in patients with PD which related to motor severity and levodopa administration 148

(2022) Paediatric acute-onset neuropsychiatric syndrome (PANS) and intravenous immunoglobulin (IVIG): Comprehensive open-label trial in Ten children, BMC Psychiatry , 22(1)

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NAD(P)H:quinone oxidoreductase 1 (NQO1), an NAD(P)H-dependent quinone reductase similar to FSP1, can synergistically promote the conversion of ubiquinone to ubiquinol, inhibiting oxidation (77, 78)