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Relationship between pulmonary matrix metalloproteinases and quantitative CT markers of small airways disease and emphysema in COPD

A., Wylam, M

3.2.3 Ferredoxin1: the regulator of protein lipoylation and diseases FDX1, an evolutionarily conserved protein characterized by the presence of FeS clusters, serves as an upstream regulator of protein lipoylation and is integral to the metabolism of steroids, cholesterol, and bile acids (170)

AIDS 33 , 16731674 (2019)
The upregulated expression of ptgs2a and acsl4a induced by FAC treatment, which was subsequently downregulated after DFO intervention, combined with the distinct expression pattern of gpx4a , may suggest that the mechanism underlying FAC-induced ferroptosis is different from that of Erastin, and the mode of ferroptosis rescue by DFO also differs from that of Fer-1

This unresolved mechanism has made DSIP a valuable research tool for studies examining peptide-mediated signaling processes and receptor-identification methodologies