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By looking at the gene expression patterns, Li's team first found that the pathway that produces vitamin B12 was significantly altered in the skin bacteria of people with acne, compared with the skin bacteria of people without acne

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While these immediate effects can be encouraging, they are often short-lived unless supported by regular injections and other complementary treatments or lifestyle changes

These mechanisms are described as research areas, not clinical outcomes

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Additionally,certain medications that many patients take before and after surgery can decrease vitamin B 12 absorption and stores in the body