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Thiamine is integral to the biochemistry of the nervous system, serving primarily as a coenzyme in key enzymatic reactions associated with energy metabolism, particularly the conversion of carbohydrates into usable energy (, , )

A cross-sectional study of 700 community-living, physically disabled women over the age of 65 found that vitamin B 12 -deficient women were twice as likely to be severely depressed as non-deficient women (97)

F., Onishi, K., Buford, D., Peng, J., Mahmood, A., et al

Prevention, detection, evaluation, and management of high blood pressure in adults: synopsis of the 2017 American college of cardiology/american heart association hypertension guideline

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