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As factors contributing to underlying molecular mechanisms, HIFs activate transcription factors and signaling pathways involved in CSC self-renewal and pluripotency, including OCT4 and NOTCH 144
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Hawiger cofounded in 2014 to sponsor clinical trials of the drug.
Establishing causality requires rigorous validation proving that TCM's efficacy depends on specific intestinal barrier changes
Copper accumulation and immune-related effects remain understudied
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