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Nat Commun 15, 2053

also performed analysis of correlation between the plasma H 2 S level and severity of COVID-19 course (estimated by cardiac injury, thrombosis and inflammatory) and found an increase in total H 2 S level in patients with severe course of COVID-19 compared with the patients with mild-to-moderately severe course of the illness [144]

I believe there are many people who have experienced similar reactions
Opioid-Induced Hyperalgesia and Allodynia Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain

Oxid Med Cell Longev (2022) 2022:1052699
C.Dennison-HimmelfarbC.HandlerJ.et al