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Increased adiponectin also reduces blood glucose levels and improves insulin sensitivity, appetite control, central fat distribution (smaller waist size) as well as muscle regeneration, thus acting as a protective factor to prevent loss of muscle mass

Incidence of type II diabetes in chronic obstructive pulmonary disease: a nested case-control study

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Further studies are indicated

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Some researchers explore microdosing approaches, where they stay below the standard starting dose or use doses between the established tiers