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[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Schroder T.H., Tan A., Mattman A., Sinclair G., Barr S.I., Vallance H.D., Lamers Y

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The CNS GLP- 1 receptors are not necessary for the physiological regulation of blood glucose levels by endogenous GLP- 1 or the pharmacological control of glucose homeostasis that depends on GLP- 1 receptors, although further research is needed to investigate the possible role of GLP- 1 receptors expressed outside the beta cell, including within the enteric and peripheral nervous systems, in improving beta cell function through enteral glucose mediation [70, 84]

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Fasting activation of AgRP neurons requires NMDA receptors and involves spinogenesis and increased excitatory tone

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