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10.1016/j.biopsych.2019.08.016 99

The aforementioned study showed that Alda-1 effectively increases activity of both the ALDH2 1*2 and ALDH2 2*2 variants, bringing them closer to the activity levels of wild-type ALDH2

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After oxidative stress in neocortical neurons, KB are neuroprotective by inducing expression of mitochondrial uncoupling proteins (UCP) which reduce ROS production (69, 108)

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