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Description
Biochemically, the cobalt center can take part in both two-electron and one-electron reductive processes to access the "reduced" (B 12r , +2 oxidation state) and "super-reduced" (B 12s , +1 oxidation state) forms

For a large portion of the population, that conversion simply doesnt happen efficiently
In Australia it is available only as a compounded preparation through prescription pharmacies

B12 shots are safe for most people, but those with certain health conditions should consult a doctor before starting treatment

Patel, R

Omitting both JW and JZ on any J-code line creates a systematic compliance exposure
