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Wang Y, Ning Y, Alam GN, Jankowski BM, Dong Z, Nr JE, Polverini PJ (2013) Amino acid deprivation promotes tumor angiogenesis through the GCN2/ATF4 pathway
INTRODUCTION The brain relies on substantial energy to maintain signaling and housekeeping functions

To account for potential drop-outs, 30 subjects were enrolled

In preclinical CNS models, multiple strategies targeting the NLRP3 inflammasome axis have shown promise
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[DOI] [PMC free article] [PubMed] [Google Scholar] Zheng S, Yumei F, Chen A

AEs leading to trial product discontinuation occurred in 6/90 (7%) participants in the CagriSema 2.4 mg/2.4 mg group, 11/93 (12%) participants in the CagriSema 1 mg/1 mg group, and 1/91 (1%) in the placebo group
