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The mortality rate of rats in the PENs-induced AD groups within 30 min was over 75%, and the rats died within 18 min after challenged, while rats in the BSA group did not die within 30 min (see Supplementary Tab

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Decreased GPX3 activity in the plasma of patients with cerebral thrombotic disorder leads to high ROS levels and rapid nitric oxide inactivation, whereas exogenous GPX3 supplementation in patients plasma can reverse nitric oxide-mediated platelet inhibition, offering protection against thrombotic disorder [195]

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