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however, this study suggests that despite the potential for human exposure to 1,4-dioxane from consumer products or impacted public drinking water, persistent and/or continuous exposure to the general population is infrequent, continuously lower than would result in a serum level of 0.5 ng/mL, or nonexistent altogether

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However, for those with mild dietary deficiencies and intact absorption mechanisms, high-dose oral tablets can often be sufficient, albeit with potentially slower results