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Some people may experience mild side effects such as gastrointestinal discomfort, headache, or allergic reactions

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Long COVID, formally defined as symptoms persisting beyond 12 weeks after acute infection, affects an estimated 10 to 30% of people who contract COVID-19

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Further research is needed to elucidate the basic mechanism underpinning T and B-cell recruitment into an immune response, to examine antibody affinity maturation and to identify the determinants of the immunodominance hierarchy for T and B-cell epitopes, which ultimately may enable vaccine antigens to be rationally designed to induce broadly targeted immunity