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Controlling the role of BPC 157 likely involves its particular interaction with the major systems involved in wound healing, such as the NO-system (counteracted harmful events, arising from either NO-blockade or NOS-substrate application) (Sikiric et al., 2014) and the prostaglandins system (i.e., large extent of the counteracted NSAIDs toxicity (Sikiric et al., 2013) as well as counteracted developing and already formed adjuvant arthritis in rats (Sikiric et al., 1997c))

4.3.1 Evidence quality classification Current research can be categorized into three evidence grades based on methodological rigor and reproducibility

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Non-uniform refinement (C2 symmetry) was used to obtain ATD structures at 3.30 (partially ruptured state 1) and 3.52 (partially ruptured state 2) resolution