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Description
Yang, K., Doan, M

two sides to every story

The thioredoxin independent isoform of chloroplastic glyceraldehyde-3-phosphate dehydrogenase is selectively regulated by glutathionylation

It also offers anti-aging skin benefits, including the stimulation of collagen and elastin production, which improves skin texture, firmness, and hydration

This early preclinical report demonstrates proof-of-principle that NMDAR antagonists may represent a new class of antidepressants
The recent EMA guidance emphasized routine use of sentinel dosing within each dosing cohort, for both single and multiple dosing, and suggested that clear scientific rationale should be available if this approach is not adopted.2 Decisions regarding dose escalation require balancing safety risks to individual subjects against the risks of failing to define the correct dose range to be used in subsequent studies, or worse yet abandoning development of a potentially useful drug
