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doi: 10.1016/0041-008X(71)90235-3

The IGF1R binds IGF1 and IGF2 with high affinity and the IR binds insulin with high affinity

The GH/IGF-1 axis in obesity: physiological and pathological aspects

FEBS Letters, 238(2), 343-346

But beyond the usual suspects, theres a deeper root thats frequently missednutritional imbalances

It modulates inflammation by regulating the production of pro-inflammatory and anti-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-) and interleukin-10 (IL-10) (Drge & Breitkreutz, 2000)
