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A final volume of 6 l click reaction mixture was added per 100 l lysate and shaken for 1 h at room temperature before quenching with 5 mM EDTA

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COVID-19 neurotropism and PD: exploring the links The CNS has been disrupted by COVID-19 in a variety of ways, including direct SARS-CoV-2 invasion of neuronal cells, huge inflammatory elements driven by severe systemic inflammation flowing into brains, respiratory failure linked brain ischemia, etc [18,19,20]