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The second is pharmacological: what side effects, treatment burden, and long-term trade-offs come with using medication to push levels that low

Similar to VEGF-C, VEGF-D can bind and activate the VEGFRs 2 and 3 (41, 42)

Exposure to acute stress also induces cognitive impairments [56], but its effects in mice with compromised glutamate neurotransmission have not been thoroughly studied

*Correspondence: Richard Eugene Frye, Arkansas Childrens Hospital Research Institute, Slot 512-41B, 13 Childrens Way, Little Rock, AR 72202, USA e-mail: [email protected] This article was submitted to Child and Neurodevelopmental Psychiatry, a section of the journal Frontiers in Pediatrics

103 In one retrospective population study, women who had taken conventional hormone replacement therapy (HRT) for menopausal symptoms had a 99% lower risk of developing BPPV compared with those who did not