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A model of H 2 O 2 -induced cell death in SK-N-SH human neuroblastoma cells was evaluated, in which morronoside protected cells from oxidative damage by inhibiting ROS production while suppressing Bcl-2-associated X protein (Bax), stimulated the expression of Bcl-2 and blocking apoptosis [147]

In a Phase II trial in pancreatic cancer patients, oral curcumin was well tolerated and showed some biological activity in a subset of patients, despite low systemic absorption (Dhillon et al., 2008)

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I K Quantitative analyses of MDA, GSH, and non-heme iron

Ryter SW (2021) Significance of heme and heme degradation in the pathogenesis of acute lung and inflammatory disorders