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Both are well-studied individually in preclinical models

[DOI] [PubMed] [Google Scholar] 198

Gunawardane LS, Saito K, Nishida KM, Miyoshi K, Kawamura Y, Nagami T, et al

I really am hoping that this will help

The choice really depends on what the experiment needs and both routes should be weighed carefully to hit research goals accurately
