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The development of drug resistance is a challenge for the use of adjuvant therapies in breast cancer patients [69], and studies suggest that ROS may play an important role in the production of drug-resistant cells [70]

At the interface between those two trimers, close to the two-fold axis, two independently ordered phospholipid molecules could be resolved (here modelled as di-stearoyl-3-sn-phosphatidylcholine) facing opposite sides of the membrane (Fig

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