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The angiogenesis and disruption of liver vascular architecture have been linked to progression to cirrhosis and liver cancer in chronic liver diseases, which contributes to both increased hepatic vascular resistance and portal hypertension and decreased hepatocyte perfusion [119,120,121]

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Adult Dosing Dosage may vary based on different medical indications: For local anesthesia, the maximum dose for infiltration is 4.5mg/kg