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H.ZhouJ.et al

T.JohnsonJ
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First-in-human evaluation of the novel mitochondrial complex I inhibitor ASP4132 for treatment of cancer

Vitamin B12, chemically known as Cobalamin, is a water-soluble vitamin that plays a crucial role in many essential bodily functions particularly red blood cell formation, nervous system and brain function, DNA synthesis, and energy metabolism

A group of studies support that an imbalance of SAMe metabolism, caused by the deficiency of B vitamins (folate, vitamin B 12 , and vitamin B 6 ), leads to decreased availability of donor methyl groups as associated with NTDs [78, 79]