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Wrinkle reduction: Particularly around the eyes and forehead
An EKG should be obtained before taking macrolides, especially if used in combination with other medications that can affect the QT interval (i.e., PPIs, SSRIs, many psychiatric medications, nausea medication like Zofran, or hydroxychloroquine)

LE Moore, P Brennan, S Karami, et al
Therapeutic Potential of Emerging NAD+-Increasing Strategies for Cardiovascular Diseases

As a control, serum samples from cyno-374 (FIG

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