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Methylmalonic acid (MMA) and homocysteine : These biomarkers rise when B12 levels are low, often before serum B12 drops, helping to detect deficiencies
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Furthermore, the blood-brain barrier (BBB) is an insurmountable obstacle for brain drug delivery
L., Guo, E., Mauk, E
Sbihi H, Boutin RC, Cutler C, Suen M, Finlay BB, Turvey SE
