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Agents can bind and couple with MRGPRX2, which stimulates phosphorylation cascades, augments intracellular calcium levels, and induces degranulation of mast cells
Int J Genomics 2014:701596

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160 However, L-methylfolate can be an effective alternative to folic acid, with some potential advantages, particularly in people with MTHFR gene variants (see below)

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