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2 / mouse RBC features and reduces erythroid vesicles release

Coppock, D., Kopman, C., Gudas, J

Carolina, E

A.LevinaV.et al

[513] extensively review the involvement of BBB breakdown and dysfunction in neurological deficits and other pathologies, including chronic conditions (Alzheimer's disease, Parkinsons disease, amyotrophic lateral sclerosis, and multiple sclerosis), as well as acute CNS disorders such as stroke, traumatic brain injury, spinal cord injury, and epilepsy

The stimulated astrocytic GSH export induced by these compounds is prevented by inhibition of Mrp1, demonstrating that this transporter mediates the druginduced stimulated GSH export, while the basal GSH export is only inhibited by around 60% in the presence of the Mrp1 inhibitor MK571 (Hirrlinger et al