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This mental disorder is composed of cognitive, behavioral, and emotional disorders, and to be diagnosed with schizophrenia, patients should have two (or more) of the following negative symptoms for a minimum of six monthsdisorganized speech, grossly disorganized or catatonic behaviorand at least one positive symptom [3]

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Several mechanisms within the TME have been implicated in the resistance to anti-PD therapy, such as loss of neoantigens and low expression of PD-L1 [5]

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Skin health is cumulative