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Atkuri KR, Manovani JJ, Herzenberg LA, Herzenberg LA

Acknowledgments This paper was financially supported by the Estonian Science Foundation Grants no

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Identification, genomic organization and expression pattern of glutathione S-transferase in the silkworm, Bombyx mori

If we assume 40 kg of tissue with an average of 2.5 mM GSH (about 750 mg/L), it means that there is 30 g of GSH in the whole body

If not neutralized by antioxidants, ROS may damage mitochondria over time, causing them to function less efficiently and to generate more damaging ROS in a self-perpetuating cycle