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This breeding strategy enabled the generation of female offspring that develop breast cancer while carrying defined mtDNA mutations at variable heteroplasmy levels (referred to as PyMT- TrnE or PyMT- ND5 models, respectively) (Fig

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Artificial intelligence (AI)-based predictive modelling can enhance inhaled drug design by integrating formulation details, aerosol behaviour and biological factors, leading to quicker and cheaper development of therapies that penetrate mucus and target the lungs 114,253,254,255,256,257,258

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