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In April 1952 he wrote to Mollie Barr, a fellow serologist, 'I am at present engaged in work with bacteriophage-antiphage interaction where the great advantage consists in sensitivity, every single virus particle that is not inactivated can be made to show up'

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The initiation of the process is catalyzed by the intracellular iron pool, which reacts with hydrogen peroxide and superoxide to produce oxygen-centered radicals