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Chem Res Toxicol 30:20462059

Effects of creatine supplementation on cognitive function of healthy individuals: a systematic review of randomized controlled trials

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The activation of AMPK broadly suppresses proinflammatory signaling pathways, including the JAK-STAT, NF-B, C/EBP, CHOP, and HIF-1 pathways, which in turn inhibits the expansion and immunosuppressive function of myeloid-derived suppressor cells (MDSCs) 42
