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Thus, ibuprofen is too hydrophilic to efficiently cross the BBB by passive diffusion

L., Johnson, J., Grant, C

Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells
Inhibiting CD147, rather than MCTs directly, disrupts lactate transport by interfering with the disulfide-bonded domains in their Ig-like C2 region, highlighting its essential role in maintaining MCT catalytic activity [221]

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