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While succinate from the matrix side increases the affinity of OGC to malate, substrates such as phenyl succinate, pyridoxal phosphate, retinoic acid, and ethanol cause inhibition of OCG

Have a B12-rich food like steak, and your serum level can rise to more than 1500 pg/mL for a short time

Retinal Diseases CAIs are used in the management of cystoid macular edema (CME) and serous retinal detachment in patients with a variety of underlying pathologies, including retinitis pigmentosa, uveitis, Sturge-Weber syndrome, morning glory syndrome, optic disc pit, and central serous chorioretinopathy

This technique originated and is known as Gerson therapy

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and thats why we sometimes need to supplement