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Future research should continue to explore the impact of commensal translocation on AD development/progression to facilitate the development of therapeutics that perhaps target the microbiota to indirectly inhibit chronic inflammation in the gut and beyond

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Furthermore, it was demonstrated that the overexpression of PINK1 promoted neuronal activity and protected neuronal integrity (Khalil et al., 2015)

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Studies show it promotes angiogenesis (new blood vessel growth), stimulates tissue regeneration in muscle, tendon, ligament, and bone, reduces inflammation, and supports gut health increasing delivery of growth factors to injury sites and reducing inflammatory cytokines